GEA ROTARY TABLET PRESSES – KTBEL https://ktbel.com Tue, 02 May 2023 04:33:33 +0000 en-US hourly 1 https://wordpress.org/?v=6.3.8 https://ktbel.com/wp-content/uploads/2023/03/cropped-logo-ktbel-32x32.png GEA ROTARY TABLET PRESSES – KTBEL https://ktbel.com 32 32 NEXGEN PRESS® 30 https://ktbel.com/product/nexgen-press-30/ Fri, 28 Apr 2023 05:53:10 +0000 https://ktbel.boostpress.space/?post_type=product&p=3172
To respond to present and future market demands, manufacturers are looking for flexible and multifunctional solutions that can handle both low and high potency active ingredients. This next generation of modular tablet presses will make machine selection easier, facilitate fast product changeovers and deliver price-performance leadership. Offering operational excellence, each NexGen Press® is intuitive, simple to use and benefits from a back-to-basics design philosophy. And, of course, like any GEA press, safety, robust functionality, support and customer service come as standard.

Flexibility comes as a standard

Available in two formats the CE-certified NexGen Press® GMP features a dust-tight enclosure for easy handling. If required, with the addition of lay flats and pressure monitoring, the GMP option can be upgraded for OEB 3 containment applications.

For example, an entry level machine can be upgraded to meet specific process requirements, such as bilayer tableting, different washing options and/or to further reduce the risk of cross-contamination, as and when required.

The NexGen Press® OEB offers both OEB 4 and 5 containment functionality and can be equipped with the BUCK® Digital Canary for real-time monitoring and/or the BUCK® (U)MC valve for contained loading.

Featuring a reduced-volume and isolated product contact area, the “double barrier” will increase operator safety. Being easier and faster to clean will mean shorter production changeovers and less downtime. The contained turret allows for a replacement to be installed in less than 1 hour. And, in an increasingly connected working environment, the presses are Industry 4.0-compatible and digitalized.

Designed to accommodate a wide range of functionalities, from general GMP production to high-containment applications, GEA has once again applied its experience and knowledge to serve the current and future pharmaceutical workforce, and the patients who depend on their products.

Furthermore, the NexGen Press® range is fully compatible with GEA’s new Digital Canary monitoring system, which both detects product leaks from contained pharmaceutical production lines and protects the health and safety of your operators.

Offering a number of plug-and-play options for applications including orodispersible, MUPS and bilayer tablets, the NexGen Press® also benefits from a user-friendly HMI with multitouch functionality, interactive digital manuals and online project documents.

A perfect blend of physical and digital

The patented Exchangeable Compression Module (ECM) concept not only provides improved containment and has a lower product-contact area compared with other models on the market, it is also WIP/WOL-compatible and facilitates fast changeovers in a small footprint, high-output rotary tablet press with multiple compression modes.

Modular by design, every NexGen Press® can be customized to fit specific applications — for now or the future — with predefined option packs. Examples include bilayer and MUPS tablets, poorly flowing powders, small volume/high yield products and those that require antisticking solutions.

Additional features such as punch face lubrication (iSpray), an intermittent cleaning system, A2D tooling for increased capacity, PAT integration and UL certification are also available.

For ongoing peace of mind, out-of-the-box training and support is always on hand. GEA offers immersive tuition via virtual reality, support intervention via a two-way remote Eyewear link, built-in preventive maintenance and a QR code system for spare parts.

]]> PERFORMA D https://ktbel.com/product/performa-d/ Fri, 28 Apr 2023 05:02:45 +0000 https://ktbel.boostpress.space/?post_type=product&p=3168

Scope

Created for reliable, high-output operation in a competitive industry, the PERFORMA D has been designed to offer the smallest footprint per tablet produced in the market. This double-sided rotary tablet press from GEA is easy to maintain, clean and operate, and ensures the cost-effective and energy efficient production of both single and bilayer tablets.

The PERFORMA D features a large turret containing up to 106 stations, making it capable of producing up to 1,140,000 tablets per hour. It is the machine of choice for high-volume applications when minimal downtime and high quality are key.

Unique to the PERFORMA D and a key differentiator from other available tablet presses is the turret enclosure. The exchangeable turret is encased in a barrier system that, compared with standard machines, provides higher levels of operator protection, enables rapid changeovers and also supports GMP-compatible production. A further benefit is the ability to perform intermediate dry cleans during extended manufacturing campaigns.

Featuring a longer, PAT-compatible double-paddle forced powder infeed system that maximizes output, the PERFORMA D also benefits from an anti-bridging agitator that keeps the powder column above the paddle feeder constant, resulting in a uniform pressure and reduced weight variation.

The press comes fitted with a three- or four-way tablet chute for both manual and automated station sampling. The design is offering easy, tool-free removal that facilitates both cleaning and changeovers.

Features

  • Turret enclosure concept
  • Multiple compression modes
  • Programmable dwell times at pre-compression and main compression
  • Weight control by displacement or force measurement
  • Maximized length of the powder feeding unit
  • Bilayer production capable
  • Small footprint

Main Benefits

  • Robust, flexible and reliable, high-output operation
  • Fast and easy (interbatch) cleaning
  • Higher levels of operator protection
  • Enhanced tablet quality
  • Reduced weight variation (resulting in a more consistent drug delivery)
  • Individual weight control for both layers of a bilayer tablet
  • User friendly, intuitive MC5 operating system

Bilayer Production: The GEA Way

The PERFORMA D manufactures bilayer tablets using a unique GEA process: it measures the weight of each layer independently to ensure the correct drug delivery profile; however, most tablet presses can only accurately assess weight when a high force is applied. High forces result in dense tablets that are difficult to bond together, making separation of the layers, or capping, almost inevitable.

 

GEA’s double-sided tablet presses have been specifically designed and developed for the high-speed production of quality bilayer tablets and provide

  • displacement weight monitoring/control for the accurate and independent weight control of the individual layers
  • low compression force exerted on the first layer to avoid capping and separation of the two individual layers
  • increased dwell time at pre-compression of both first and second layer to provide better de-aeration and defined hardness at maximum turret speed
  • maximum prevention of cross-contamination between the two layers
  • a clear visual separation between the two layers
  • maximized yield.

Data Collection

The MULTI-CONTROL 5 (MC5) is the latest GEA control system for rotary presses. The system’s hardware and software are designed to allow for full compliancy with the 21 CFR PART 11 guideline. It is a fully automated monitoring, control and reporting system based on a PLC/PC hardware configuration. MC5 features include

  • standalone PC application (all-in-one), independent from Windows operating system
  • Microsoft Windows 10 operating system
  • 21.5” HD multi-touch widescreen
  • industrial IPC
  • Siemens PLC (S7-1500) for machine control
  • software design and lifecycle management according to GAMP and internal ISO procedures (QMS)
  • integrated help system, with user manual, machine operation manual, mechanical and electrical drawings.

The HMI panel can be moved to either side of the unit for increased flexibility and positioning.

Technical Specifications

The PERFORMA D is available for D35, D, B, BB, BBS and A2D tooling

Tooling (EUR or TSM) D35 D B BB BBS    A2D
Max. tablet diameter/lenght [mm] 35 25,4 16 (L=19) 13 (L=14,3) 11 11
Punch body diameter [mm] 35 25,4 19 19 19 12
Outside die diameter [mm] 52 38,1 30,16 24 22 38,1
Die height [mm] 23,81 23,81 22,22 22,22 22,22 23,81
Number of punch positions 39 53 67 81 89 106
Max. fill depth [mm] 20 (25) 20 19 19 19 19
Top punch penetration [mm] 1 to 4
Max. pre-compression force [kN] 10 (under extended dwell time)
Max. main compression force [kN] 100
Max. output capacity 350.000 540.000 722.000 875.000 1.069.000 1.272.000
Electrical requirements 3phase+PE – 380 / 400 / 415 / 460 / 480 V – 50Hz / 60Hz
(nominal consumption 16 kVa; power installed 32,4 kVA)
Compressed air requirements clean & dry – 7-8 bar – 500Nl/min peak – 100 Nl/min average
Dust extraction requirements 150 m³/h at 15 mbar (single layer) – 230 m3/h at 50 mbar (bi-layer)
Operating conditions temperature 15 – 40 °C ; relative humidity < 60%
Machine dimensions & weight W = 1.450 mm x D = 1.450 mm (+ max 865 extended HMI arm) x H = 2.245 m – 5.700 kg
(excluding electrical cabinet: W 810 x D 510 x H 2.150 ; weight +/- 300 kg)
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