Main features
Designed for production-scale functionality, special mixing tools are available for specific applications, as well as a jacketed bowl for temperature control during the process. And, as bowl shape, mixing tools and process parameters are exactly the same, all processes running on the Gral range can be immediately transferred to the UltimaGral and single-pot UltimaPro granulators without changing any parameters. With bowl capacities of 10–1200 L (useful bowl content up to 2/3 of gross capacity), the UltimaGral range can cover all requirements after the formulation stage. From clinical batch production for scale-up trials to large-scale production for marketed products, scalability is key to the system’s success. The most important features of this design are the top-driven mixer and chopper, the optimized design to ensure easy cleaning & GMP compliance, and the through-the-wall installation of the larger machines.
Additional features
-Easy to wash-in-place (WIP)
-Built to GMP-standards
-Total containment of the product
-Variable speed chopper and impeller
-Operator control panel on the machine
-Automation/PC/PLC controls
-Controlled product discharge
-Automatic end point detection with PROCOLL-software
-Explosion proof design
-Heating and cooling units
-Fill-O-Matic (vacuum) or gravity loading system.
-EC type approved for pressure shock resistant integrated systems and 16-bar pressure shock resistant high shear granulators
Concealed services
The design of the UltimaGral ensures that lines and hoses for the utilities on the machine (water, electricity, hydraulics, etc.) are concealed in the machine encasement. This creates an uncluttered working space and avoids hoses being run to the machine within the process area.